Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718945 | 0.90 | PIK3CG (0.71) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL10818692 | 0.88 | PIK3CG (0.65) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL4762296 | 0.86 | KDM4E (0.65) | ALDH1A1KDM4EKMT2AATMTDP1 | |
| SCHEMBL4761515 | 0.84 | ALDH1A1 (0.59) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL4717938 | 0.83 | PIK3CG (0.72) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL10920126 | 0.82 | KDM4E (0.59) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL4717846 | 0.80 | KDM4E (0.69) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL10919722 | 0.80 | KDM4E (0.63) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL10807312 | 0.79 | KDM4E (0.62) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL10809245 | 0.79 | KDM4E (0.77) | PIK3CGPIK3CDPIK3R1PIK3CAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230235-B1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RES SWEDEN AB (SE) | 2008-06-11 | — | — | EP | claimed |