Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 10/20 | 0.35 |
| ▸ | CA2 | P00918 | 10/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10219073 | 0.76 | EPHX2 (0.44) | LMNACA1CA2TERTADRA2C | |
| SCHEMBL4719609 | 0.70 | — | — | |
| SCHEMBL10986583 | 0.67 | — | — | |
| SCHEMBL11874918 | 0.67 | HDAC4 (0.39) | LMNACA1CA2TERTTAAR1 | |
| SCHEMBL10826892 | 0.65 | MEN1 (0.33) | LMNA | |
| SCHEMBL4719477 | 0.64 | KMT2A (0.33) | LMNACA1CA2 | |
| SCHEMBL3973741 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL11878758 | 0.63 | KMT2A (0.32) | LMNACA1CA2 | |
| SCHEMBL28005472 | 0.63 | — | — | |
| SCHEMBL10943194 | 0.63 | CA2 (0.33) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839192-B1 | AN IMPROVED IMMOBILIZED PENICILLIN G ACYLASE | DSM IP ASSETS BV (NL) | 2008-12-10 | — | — | EP | disclosed |
| EP-1416054-B1 | Simple enzymatic process for preparing cefazolin | BIOFERMA MURCIA S A (ES) | 2005-08-17 | — | — | EP | disclosed |
| EP-1556500-A1 | SIMPLE ENZYMATIC PROCESS FOR PREPARING CEFAZOLIN | Bioferma Murcia, S.A. (ES) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039997-A1 | SIMPLE ENZYMATIC PROCESS FOR PREPARING CEFAZOLIN | BIOFERMA MURCIA, S.A. (ES) | 2004-05-13 | — | — | WO | disclosed |
| EP-1416054-A1 | Simple enzymatic process for preparing cefazolin | Bioferma Murcia, S.A. (ES) | 2004-05-06 | — | — | EP | disclosed |
| US-6060268-A | PROVIDES A HIGHER SYNTHESIS/HYDROLYSIS RATIO; FOR PRODUCTION OF BETA-LACTAM DERIVATIVES SUCH AS CEPHALOSPORINS AND PENICILLINS BY REACTING AN AMINO BETA-LACTAM WITH AN ACYLATING AGENT IN THE PRESENCE OF THE IMMOBILIZED ENZYME | GIST-BROCADES B.V. (NL) | 2000-05-09 | — | — | US | disclosed |
| EP-0839192-A1 | AN IMPROVED IMMOBILIZED PENICILLIN G ACYLASE | GIST-BROCADES B.V. (NL) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997004086-A1 | AN IMPROVED IMMOBILIZED PENICILLIN G ACYLASE | GIST-BROCADES B.V. (NL) | 1997-02-06 | — | — | WO | disclosed |