Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721217 | 0.94 | PDE4A (0.33) | UGCGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4721508 | 0.93 | ACACB (0.35) | ACACBUGCGNOTUMFFAR1PDE4A | |
| SCHEMBL4723325 | 0.89 | NOTUM (0.36) | ACACBUGCGNOTUMFFAR1PDE4A | |
| SCHEMBL4722182 | 0.89 | NOTUM (0.36) | ACACBUGCGNOTUMFFAR1PDE4A | |
| SCHEMBL4722304 | 0.89 | NOTUM (0.36) | ACACBUGCGNOTUMFFAR1PDE4A | |
| SCHEMBL4718837 | 0.89 | LIPG (0.39) | ACACBUGCGNOTUMFFAR1PDE4A | |
| SCHEMBL4719026 | 0.88 | ACACB (0.38) | ACACBUGCGNOTUMFFAR1F10 | |
| SCHEMBL4722323 | 0.88 | PDE4A (0.36) | ACACBUGCGNOTUMFFAR1PDE4A | |
| SCHEMBL4721893 | 0.88 | LIPG (0.35) | ACACBUGCGNOTUMFFAR1PDE4A | |
| SCHEMBL4720191 | 0.87 | ACACB (0.37) | ACACBUGCGNOTUMFFAR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |