Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.34 |
| ▸ | LIPC | P11150 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719026 | 0.96 | ACACB (0.38) | ACACBNOTUMKMT2ALIPGLIPC | |
| SCHEMBL4721893 | 0.91 | LIPG (0.35) | ACACBNOTUMLIPGLIPCUGCG | |
| SCHEMBL4718837 | 0.89 | LIPG (0.39) | ACACBNOTUMLIPGLIPCUGCG | |
| SCHEMBL4721508 | 0.88 | ACACB (0.35) | ACACBNOTUMLIPGLIPCUGCG | |
| SCHEMBL4722947 | 0.88 | MAPT (0.39) | ACACBNOTUMKMT2AKDM4EUGCG | |
| SCHEMBL4719633 | 0.87 | ACACB (0.35) | ACACBNOTUMLIPGUGCGFFAR1 | |
| SCHEMBL4722323 | 0.85 | PDE4A (0.36) | ACACBNOTUMUGCGFFAR1F10 | |
| SCHEMBL4722220 | 0.85 | GRIA2 (0.35) | ACACBUGCGSCDGRIA2F10 | |
| SCHEMBL4724110 | 0.84 | SMPD3 (0.40) | ACACBUGCGF10 | |
| SCHEMBL4720529 | 0.84 | SMPD3 (0.40) | ACACBUGCGF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |