Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | CCR1 | P32246 | 7/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719706 | 1.00 | P2RX7 (0.35) | P2RX7F10CCR1F2ALK | |
| SCHEMBL4722983 | 0.95 | P2RX7 (0.36) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4722990 | 0.95 | P2RX7 (0.36) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4719639 | 0.95 | F10 (0.37) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4719634 | 0.95 | F10 (0.37) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4721375 | 0.94 | F10 (0.34) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4721377 | 0.94 | F10 (0.34) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4724775 | 0.93 | NOTUM (0.35) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4724779 | 0.93 | NOTUM (0.35) | P2RX7F10CCR1F2CXCR3 | |
| SCHEMBL4720716 | 0.92 | F10 (0.36) | P2RX7F10F2CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |