Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718845 | 0.90 | GPR119 (0.63) | GPR119CYP2C9 | |
| SCHEMBL4719030 | 0.89 | GPR119 (0.67) | GPR119CYP2C9 | |
| SCHEMBL288892 | 0.89 | GPR119 (1.00) | GPR119CYP2C9KCNH2 | |
| SCHEMBL4721616 | 0.88 | GPR119 (0.62) | GPR119CYP2C9KCNH2 | |
| SCHEMBL4720557 | 0.88 | GPR119 (0.61) | GPR119CYP2C9 | |
| SCHEMBL4722464 | 0.88 | GPR119 (0.60) | GPR119CYP2C9 | |
| SCHEMBL4722426 | 0.87 | GPR119 (0.60) | GPR119CYP2C9KCNH2 | |
| SCHEMBL4720782 | 0.86 | GPR119 (0.58) | GPR119CYP2C9 | |
| SCHEMBL4722205 | 0.86 | GPR119 (0.59) | GPR119CYP2C9 | |
| SCHEMBL4719427 | 0.86 | GPR119 (0.59) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756084-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2008-11-26 | — | — | EP | claimed |