SCHEMBL4722464

SCHEMBL4722464

CC(C)OC(=O)ON1CCC(Oc2cc(Nc3ccc(S(C)(=O)=O)cc3)ncn2)CC1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.60
CYP2C9 P11712 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386797 0.88 GPR119 (0.77) GPR119CYP2C9
SCHEMBL4719718 0.88 GPR119 (0.79) GPR119CYP2C9
SCHEMBL4723387 0.87 GPR119 (0.49) GPR119
SCHEMBL4721011 0.85 FLT3 (0.49) GPR119
SCHEMBL4723183 0.84 GPR119 (0.46) GPR119
SCHEMBL4723224 0.83 GPR119 (0.46) GPR119
SCHEMBL4722122 0.83 GPR119 (0.51) GPR119CYP2C9
SCHEMBL4721907 0.83 GPR119 (0.47) GPR119
SCHEMBL4721899 0.83 GPR119 (0.46) GPR119
SCHEMBL4718772 0.83 GPR119 (0.51) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1756084-B1 SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO ARENA PHARM INC (US) 2008-11-26 EP claimed