Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.41 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385517 | 0.81 | NUDT1 (0.49) | SLC2A1NUDT1BCHETRPC3TRPC4 | |
| SCHEMBL4718040 | 0.80 | CYP2C9 (0.45) | NUDT1PDE5ADAGLAKMT2AMETAP2 | |
| SCHEMBL4714905 | 0.80 | BCHE (0.65) | SLC2A1BCHETRPC3TRPC4TRPC5 | |
| SCHEMBL5399298 | 0.77 | NUDT1 (0.44) | SLC2A1NUDT1PDE5ADAGLAKMT2A | |
| Hydrochloric Acid SCHEMBL6251675 | 0.76 | NUDT1 (0.43) | SLC2A1NUDT1PDE5ADAGLAKMT2A | |
| SCHEMBL4714500 | 0.71 | FAAH (0.40) | DAGLA | |
| SCHEMBL178884 | 0.71 | SLC2A1 (0.56) | SLC2A1 | |
| SCHEMBL19377809 | 0.71 | SLC2A1 (0.52) | SLC2A1TP53 | |
| SCHEMBL3997802 | 0.71 | PDE5A (0.50) | NUDT1PDE5ARIPK1KMT2AMETAP2 | |
| SCHEMBL28284325 | 0.71 | TP53 (0.63) | NUDT1PDE5ADAGLAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216230-B1 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2008-04-23 | — | — | EP | disclosed |