Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 1/20 | 0.53 |
| ▸ | CALCRL | Q16602 | 18/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.52 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717363 | 0.94 | CALCRL (0.56) | CALCACALCRLCYP3A4 | |
| SCHEMBL4716878 | 0.94 | CALCRL (0.57) | CALCACALCRLCYP3A4 | |
| SCHEMBL4718734 | 0.92 | CALCRL (0.62) | CALCRLCYP3A4 | |
| SCHEMBL4721310 | 0.91 | CALCRL (0.52) | CALCACALCRLCYP3A4 | |
| SCHEMBL3307869 | 0.91 | CALCA (0.63) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL4720343 | 0.90 | CALCRL (0.52) | CALCACALCRLCYP3A4 | |
| SCHEMBL6223278 | 0.89 | CALCRL (0.54) | CALCACALCRLCYP3A4 | |
| SCHEMBL4720521 | 0.88 | CALCRL (0.59) | CALCACALCRLCYP3A4RAMP1 | |
| SCHEMBL3307013 | 0.86 | CALCRL (0.67) | CALCACALCRLCYP3A4 | |
| SCHEMBL4717484 | 0.85 | CALCRL (0.56) | CALCACALCRLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | claimed |
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1558600-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004037810-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-06 | — | — | WO | disclosed |