Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720511 | 1.00 | SLC40A1 (0.35) | SLC40A1P2RX7SOS1TACR1PIM1 | |
| SCHEMBL4724242 | 1.00 | SLC40A1 (0.35) | SLC40A1P2RX7SOS1TACR1PIM1 | |
| SCHEMBL4722529 | 0.92 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3ARORC | |
| SCHEMBL4722535 | 0.92 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3ARORC | |
| SCHEMBL4721474 | 0.91 | SOS1 (0.34) | P2RX7SOS1PDE3BPDE3ARORC | |
| SCHEMBL4721469 | 0.91 | SOS1 (0.34) | P2RX7SOS1PDE3BPDE3ARORC | |
| SCHEMBL4719872 | 0.88 | SLC40A1 (0.33) | SLC40A1PIM1 | |
| SCHEMBL4722421 | 0.88 | SLC40A1 (0.33) | SLC40A1PIM1 | |
| SCHEMBL4719871 | 0.88 | SLC40A1 (0.33) | SLC40A1PIM1 | |
| SCHEMBL4719110 | 0.87 | TRPV1 (0.34) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |