Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723702 | 0.91 | ALK (0.40) | LMNAMAPTGAASMN1; SMN2CYP2C9 | |
| SCHEMBL4724509 | 0.89 | PDE4A (0.41) | LMNAMAPTSMN1; SMN2PDE4APDE4B | |
| SCHEMBL4724195 | 0.89 | F10 (0.42) | MAPTALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL4722495 | 0.88 | F10 (0.44) | MAPTHSD17B10CYP2C9ALDH1A1NPSR1 | |
| SCHEMBL4722762 | 0.86 | F10 (0.39) | MAPTGAASMN1; SMN2HSD17B10CYP2C9 | |
| SCHEMBL4721533 | 0.86 | NOTUM (0.39) | MAPTSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL4721093 | 0.85 | PDE4A (0.37) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4722787 | 0.85 | NOTUM (0.48) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4722706 | 0.85 | NOTUM (0.48) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4719505 | 0.85 | PDE4A (0.35) | MAPTSMN1; SMN2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |