Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724195 | 0.94 | F10 (0.42) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4724509 | 0.94 | PDE4A (0.41) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4722495 | 0.93 | F10 (0.44) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4721093 | 0.89 | PDE4A (0.37) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL14101702 | 0.89 | F10 (0.40) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4723702 | 0.88 | ALK (0.40) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL4722548 | 0.87 | PDE4A (0.37) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4721967 | 0.87 | PDE4A (0.38) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4722660 | 0.86 | PDE4A (0.37) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL14102036 | 0.86 | F10 (0.40) | F10F2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |