Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720515 | 0.91 | LMNA (0.38) | ALKMAPTCYP2C9HDAC6USP2 | |
| SCHEMBL4724195 | 0.91 | F10 (0.42) | MAPTALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL4724509 | 0.91 | PDE4A (0.41) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4722495 | 0.90 | F10 (0.44) | MAPTCYP2C9ALDH1A1NPSR1PDE4A | |
| SCHEMBL4722762 | 0.88 | F10 (0.39) | MAPTCYP2C9USP2MEN1ALDH1A1 | |
| SCHEMBL4721093 | 0.88 | PDE4A (0.37) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4722548 | 0.86 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14101702 | 0.86 | F10 (0.40) | MAPTALDH1A1NPSR1PDE4APDE4B | |
| SCHEMBL4721967 | 0.86 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4722276 | 0.85 | UGCG (0.36) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |