⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18428478 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL706142 | 0.67 | CA4 (0.42) | — | |
| SCHEMBL3791882 | 0.63 | — | — | |
| SCHEMBL6677287 | 0.62 | — | — | |
| SCHEMBL2600449 | 0.61 | TP53 (0.34) | — | |
| SCHEMBL15353596 | 0.61 | HTR1A (0.45) | — | |
| SCHEMBL7060378 | 0.61 | — | — | |
| SCHEMBL17403302 | 0.61 | CA12 (0.32) | — | |
| SCHEMBL1694599 | 0.61 | — | — | |
| SCHEMBL7061824 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053944-B1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR | SHINETSU CHEMICAL CO (JP) | 2021-10-06 | — | — | EP | claimed |
| US-9708350-B2 | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-07-18 | — | — | US | claimed |
| US-20210347941-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS (US) | 2021-11-11 | — | — | US | disclosed |
| EP-3053944-B1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR | SHINETSU CHEMICAL CO (JP) | 2021-10-06 | — | — | EP | disclosed |
| EP-3434713-B1 | METHODS OF PREPARING AND PURIFYING POLYALKYLENE GLYCOL DERIVATIVES | SHINETSU CHEMICAL CO (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10941248-B2 | Methods for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS (US) | 2021-03-09 | — | — | US | disclosed |
| US-10836861-B2 | Methods of preparing and purifying polyalkylene glycol derivative | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| US-10472377-B2 | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20190055354-A1 | METHODS FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS | 2019-02-21 | — | — | US | disclosed |
| EP-3434713-A1 | METHODS OF PREPARING AND PURIFYING POLYALKYLENE GLYCOL DERIVATIVES | Shin-Etsu Chemical Co., Ltd. (JP) | 2019-01-30 | — | — | EP | disclosed |
| US-20190023841-A1 | METHODS OF PREPARING AND PURIFYING POLYALKYLENE GLYCOL DERIVATIVE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-01-24 | — | — | US | disclosed |
| WO-2007011802-A1 | METHOD FOR PREPARING BRANCHED FUNCTIONALIZED POLYMERS USING BRANCHED POLYOL CORES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |
| EP-1656410-A2 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | Nektar Therapeutics Al, Corporation (US) | 2006-05-17 | — | — | EP | disclosed |
| US-20060051879-A9 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOSTER HUBERT | 2006-03-09 | — | — | US | disclosed |
| US-20050054816-A1 | Method for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS | 2005-03-10 | — | — | US | disclosed |
| US-20050042771-A1 | Identifying non-drug targets; use in drug design for improving knowledge of drug-target and drug-non-target interactions, so that drug adverse reactions can be reduced or eliminated in drugs such as troglitazone, rosiglitazone, pioglitazone, methotrexate, atorvastatin, celecoxib, rofecoxib, cerivastatin | CAPROTEC BIOANALYTICS GMBH (DE) | 2005-02-24 | — | — | US | disclosed |
| WO-2005010075-A2 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-2004064972-A9 | CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS | HK PHARMACEUTICALS INC (US) | 2004-09-16 | — | — | WO | disclosed |
| WO-2003092581-A9 | CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS | HK PHARMACEUTICALS INC (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20030119021-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2003-06-26 | — | — | US | disclosed |