Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 5/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720791 | 1.00 | MTNR1A (0.36) | MTNR1AMTNR1BF10PDE2AACACB | |
| SCHEMBL4724110 | 0.93 | SMPD3 (0.40) | MTNR1AMTNR1BF10ACACBUGCG | |
| SCHEMBL4720535 | 0.93 | SMPD3 (0.40) | MTNR1AMTNR1BF10ACACBUGCG | |
| SCHEMBL4720529 | 0.93 | SMPD3 (0.40) | MTNR1AMTNR1BF10ACACBUGCG | |
| SCHEMBL4721705 | 0.91 | MTNR1A (0.42) | MTNR1AMTNR1BF10UGCGKMT2A | |
| SCHEMBL4721701 | 0.91 | MTNR1A (0.42) | MTNR1AMTNR1BF10UGCGKMT2A | |
| SCHEMBL4720911 | 0.90 | MTNR1A (0.50) | MTNR1AMTNR1BF10UGCGKMT2A | |
| SCHEMBL4720913 | 0.90 | MTNR1A (0.50) | MTNR1AMTNR1BF10UGCGKMT2A | |
| Hydrochloric Acid SCHEMBL4719632 | 0.89 | CHRM1 (0.36) | F10UGCGMCHR1 | |
| SCHEMBL4721983 | 0.87 | NOTUM (0.40) | ACACBUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |