Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | CCNC | P24863 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721143 | 1.00 | SUV39H2 (0.36) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4720392 | 0.94 | MTNR1A (0.40) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4720389 | 0.94 | MTNR1A (0.40) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4722374 | 0.87 | ITGB2 (0.37) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4722251 | 0.87 | ITGB2 (0.37) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4766491 | 0.87 | ITGB2 (0.37) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4720703 | 0.86 | ITGB2 (0.39) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4720700 | 0.86 | ITGB2 (0.39) | SUV39H2ITGB2ICAM1ITGALMTNR1A | |
| SCHEMBL4719467 | 0.86 | WDR5 (0.34) | WDR5 | |
| SCHEMBL4719042 | 0.84 | ITGB2 (0.40) | SUV39H2ITGB2ICAM1ITGALMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |