Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721242 | 0.95 | RAD52 (0.38) | KAT2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4720140 | 0.91 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL4721102 | 0.91 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL4722089 | 0.90 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL14101739 | 0.90 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL14101915 | 0.90 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL4720454 | 0.90 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL4721347 | 0.90 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL4720622 | 0.89 | AAK1 (0.34) | PDE4APDE4BPDE4CPDE4DMAPT | |
| Hydrochloric Acid SCHEMBL4720194 | 0.89 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |