Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721516 | 0.88 | ABCB1 (0.41) | NPSR1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL4720272 | 0.87 | ERN1 (0.40) | SMN1; SMN2KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL4723825 | 0.87 | NPSR1 (0.36) | SMN1; SMN2KDM4ENPSR1MEN1KMT2A | |
| SCHEMBL4722409 | 0.81 | MAPT (0.53) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL4722929 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL4721126 | 0.76 | NPC1 (0.44) | SMN1; SMN2KDM4EMEN1KMT2ASLC2A1 | |
| SCHEMBL4722411 | 0.74 | MAPT (0.38) | SMN1; SMN2KDM4ENPSR1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL4719619 | 0.72 | MAPT (0.54) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL4719536 | 0.71 | MAPT (0.51) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL4720212 | 0.71 | MAPT (0.46) | SMN1; SMN2KDM4ENPSR1MAPTALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |