Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721359 | 0.90 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL4722409 | 0.87 | MAPT (0.53) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL4723497 | 0.86 | ALDH1A1 (0.43) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL4721428 | 0.80 | PDE4B (0.41) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL4721516 | 0.80 | ABCB1 (0.41) | MAPTMEN1KMT2ANPSR1MAPK1 | |
| Hydrochloric Acid SCHEMBL4719619 | 0.79 | MAPT (0.54) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL4719253 | 0.79 | NPSR1 (0.44) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL4719536 | 0.78 | MAPT (0.51) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL4723825 | 0.77 | NPSR1 (0.36) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL4720272 | 0.77 | ERN1 (0.40) | MAPTMEN1KMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |