Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721627 | 0.93 | P2RX7 (0.36) | F10F2P2RX7NOTUMACACB | |
| SCHEMBL4766330 | 0.93 | P2RX7 (0.36) | F10F2P2RX7NOTUMACACB | |
| SCHEMBL4721632 | 0.93 | P2RX7 (0.36) | F10F2P2RX7NOTUMACACB | |
| SCHEMBL4724414 | 0.92 | P2RX7 (0.35) | F10F2P2RX7NOTUMABL1 | |
| SCHEMBL4723010 | 0.92 | P2RX7 (0.35) | F10F2P2RX7SOS1ACACB | |
| SCHEMBL4724420 | 0.92 | P2RX7 (0.35) | F10F2P2RX7NOTUMABL1 | |
| SCHEMBL4723006 | 0.92 | P2RX7 (0.35) | F10F2P2RX7SOS1ACACB | |
| SCHEMBL4721802 | 0.91 | P2RX7 (0.35) | F10F2P2RX7ACACBABL1 | |
| SCHEMBL4721808 | 0.91 | P2RX7 (0.35) | F10F2P2RX7ACACBABL1 | |
| SCHEMBL4724937 | 0.91 | F10 (0.34) | F10F2P2RX7SOS1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |