Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 11/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724420 | 1.00 | P2RX7 (0.35) | P2RX7F10F2ABL1PDE7A | |
| SCHEMBL4721851 | 0.94 | P2RX7 (0.37) | P2RX7F10F2RORC | |
| SCHEMBL4721854 | 0.94 | P2RX7 (0.37) | P2RX7F10F2RORC | |
| SCHEMBL4766330 | 0.93 | P2RX7 (0.36) | P2RX7F10F2ABL1PDE3B | |
| SCHEMBL4721632 | 0.93 | P2RX7 (0.36) | P2RX7F10F2ABL1PDE3B | |
| SCHEMBL4721627 | 0.93 | P2RX7 (0.36) | P2RX7F10F2ABL1PDE3B | |
| SCHEMBL4722615 | 0.93 | ABL1 (0.39) | P2RX7F10F2ABL1 | |
| SCHEMBL4722609 | 0.93 | ABL1 (0.39) | P2RX7F10F2ABL1 | |
| SCHEMBL4723010 | 0.93 | P2RX7 (0.35) | P2RX7F10F2ABL1PDE3B | |
| SCHEMBL4723006 | 0.93 | P2RX7 (0.35) | P2RX7F10F2ABL1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |