Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725015 | 0.96 | BRD4 (0.38) | PDE3BPDE3ADDB1CRBNRAF1 | |
| SCHEMBL4721889 | 0.88 | SMN1; SMN2 (0.32) | BRD4SCDSMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL4721552 | 0.87 | SCD (0.40) | SCDSMN1; SMN2EPHX2 | |
| SCHEMBL4723445 | 0.87 | SMN1; SMN2 (0.35) | BRAFSCDSMN1; SMN2 | |
| SCHEMBL14101911 | 0.86 | PDE4A (0.35) | SCDSMN1; SMN2 | |
| SCHEMBL14101915 | 0.86 | PDE4A (0.36) | SCDSMN1; SMN2 | |
| SCHEMBL4720454 | 0.85 | PDE4A (0.38) | SCDSMN1; SMN2 | |
| SCHEMBL4765721 | 0.85 | PDE4A (0.36) | SCDSMN1; SMN2 | |
| SCHEMBL4722084 | 0.85 | PDE4A (0.35) | SCDSMN1; SMN2 | |
| SCHEMBL4721953 | 0.84 | PDE4A (0.36) | SCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |