Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883347 | 1.00 | MCHR1 (0.53) | MCHR1KCNH2 | |
| SCHEMBL4878488 | 0.82 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL3542979 | 0.78 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL13912317 | 0.77 | MCHR1 (0.61) | MCHR1KCNH2 | |
| SCHEMBL4876379 | 0.76 | MCHR1 (0.62) | MCHR1KCNH2 | |
| SCHEMBL14535221 | 0.74 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL5256633 | 0.73 | MCHR1 (0.73) | MCHR1KCNH2 | |
| SCHEMBL14535186 | 0.72 | MCHR1 (0.71) | MCHR1 | |
| SCHEMBL12838152 | 0.72 | MCHR1 (0.69) | MCHR1 | |
| SCHEMBL14535218 | 0.72 | MCHR1 (0.58) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221107-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-09-11 | — | — | US | claimed |
| EP-1907398-A1 | THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2008-04-09 | — | — | EP | claimed |
| WO-2007011284-A1 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | WO | claimed |
| US-20080221107-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221107-A1 | Therapeutic Agents | HTT, ACHE, GRIN2A | MCHR1 1607/4885KCNH2 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.