Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876379 | 0.94 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL5633926 | 0.85 | MCHR1 (0.64) | MCHR1 | |
| SCHEMBL5635417 | 0.83 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL5636058 | 0.83 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL5634744 | 0.82 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL4883347 | 0.82 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL4722176 | 0.82 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL5634906 | 0.81 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL304471 | 0.81 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL30700953 | 0.81 | MCHR1 (0.63) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221107-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-09-11 | — | — | US | claimed |
| US-20080221107-A1 | Therapeutic Agents | ASTRAZENECA AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221107-A1 | Therapeutic Agents | HTT, ACHE, GRIN2A | MCHR1 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.