Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722220 | 0.94 | GRIA2 (0.35) | MAPTALDH1A1MAPK1ALOX15LMNA | |
| SCHEMBL4722930 | 0.90 | PDE4A (0.37) | MAPTALDH1A1ALOX15KDM4EL3MBTL1 | |
| SCHEMBL4719026 | 0.89 | ACACB (0.38) | ALDH1A1MEN1KMT2AACACBUGCG | |
| SCHEMBL4722304 | 0.89 | NOTUM (0.36) | MAPTALDH1A1MAPK1ALOX15KDM4E | |
| SCHEMBL4723325 | 0.89 | NOTUM (0.36) | MAPTALDH1A1MAPK1ALOX15KDM4E | |
| SCHEMBL4722182 | 0.89 | NOTUM (0.36) | MAPTALDH1A1MAPK1ALOX15KDM4E | |
| SCHEMBL4720191 | 0.88 | ACACB (0.37) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL4720535 | 0.88 | SMPD3 (0.40) | ACACBUGCG | |
| SCHEMBL4724110 | 0.88 | SMPD3 (0.40) | ACACBUGCG | |
| SCHEMBL4720529 | 0.88 | SMPD3 (0.40) | ACACBUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |