Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722299 | 1.00 | P2RX7 (0.35) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4724553 | 0.92 | SYK (0.37) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4720488 | 0.92 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4720492 | 0.92 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4724546 | 0.92 | SYK (0.37) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4721510 | 0.91 | P2RX7 (0.33) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4721515 | 0.91 | P2RX7 (0.33) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4719227 | 0.89 | P2RX7 (0.35) | P2RX7SOS1PDE3BPDE3ANOTUM | |
| SCHEMBL4719224 | 0.89 | P2RX7 (0.35) | P2RX7SOS1PDE3BPDE3ANOTUM | |
| SCHEMBL4723417 | 0.89 | SOS1 (0.36) | P2RX7SOS1PDE3BPDE3APHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |