Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720492 | 1.00 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3ATYRO3 | |
| SCHEMBL4721510 | 0.93 | P2RX7 (0.33) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4721515 | 0.93 | P2RX7 (0.33) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4719688 | 0.93 | GHSR (0.31) | P2RX7 | |
| SCHEMBL4722299 | 0.92 | P2RX7 (0.35) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4722296 | 0.92 | P2RX7 (0.35) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4721936 | 0.92 | SYK (0.31) | SYKITGB2ICAM1ITGAL | |
| SCHEMBL4724553 | 0.91 | SYK (0.37) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4724546 | 0.91 | SYK (0.37) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4722487 | 0.90 | P2RX7 (0.38) | P2RX7SOS1PDE3BPDE3ATYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |