Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014929 | 0.88 | KCNN4 (0.51) | KCNN4KDM4EDRD2CREBBPKMT2A | |
| SCHEMBL6014892 | 0.78 | KCNN4 (0.40) | KCNN4KDM4EDRD2CREBBPNPSR1 | |
| SCHEMBL6014925 | 0.75 | GRIA1 (0.56) | KCNN4KDM4ESQORLMNAGRIA1 | |
| SCHEMBL27735025 | 0.74 | SQOR (0.40) | KCNN4KDM4ECREBBPKMT2ASQOR | |
| SCHEMBL6014911 | 0.72 | GRIA1 (0.47) | KDM4EGRIA1GRIA3PDE4DMAPT | |
| SCHEMBL6014918 | 0.72 | GRIA1 (0.47) | KCNN4KDM4ESQORGRIA1GRIA3 | |
| SCHEMBL28775311 | 0.72 | DCTPP1 (0.45) | KCNN4KDM4EKMT2ALMNASMN1; SMN2 | |
| SCHEMBL27755574 | 0.71 | GAA (0.43) | KDM4EKMT2ANPSR1SQORLMNA | |
| SCHEMBL6014899 | 0.70 | GRIA1 (0.49) | KDM4ESQORSMN1; SMN2HSD17B10GRIA1 | |
| SCHEMBL15542327 | 0.69 | KCNN4 (1.00) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | claimed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |