Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721279 | 0.85 | CREBBP (0.52) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL14291727 | 0.78 | NPC1 (0.39) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4723720 | 0.76 | CREBBP (0.43) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4309447 | 0.76 | CREBBP (0.59) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4312331 | 0.75 | CREBBP (0.52) | CREBBPEP300MEN1KMT2ARAB9A | |
| SCHEMBL4721231 | 0.75 | CREBBP (0.45) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4724279 | 0.74 | CREBBP (0.40) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL14852475 | 0.74 | CREBBP (0.41) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL14101943 | 0.74 | CREBBP (0.44) | CREBBPEP300MEN1KMT2AICAM1 | |
| SCHEMBL4315290 | 0.74 | CREBBP (0.58) | CREBBPEP300MEN1KMT2AICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |