Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 8/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724195 | 0.90 | F10 (0.42) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL4724509 | 0.90 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL4722495 | 0.89 | F10 (0.44) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL4722762 | 0.87 | F10 (0.39) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL4724356 | 0.87 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DSOS1 | |
| SCHEMBL4723702 | 0.86 | ALK (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4766663 | 0.85 | F10 (0.44) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL4721093 | 0.85 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL14101702 | 0.85 | F10 (0.40) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL4721967 | 0.85 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |