Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722125 | 0.93 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4724313 | 0.89 | CYP1A2 (0.42) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4721837 | 0.89 | CYP1A2 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4722204 | 0.89 | CYP1A2 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4723078 | 0.88 | CYP1A2 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4723982 | 0.88 | GAA (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4721819 | 0.87 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4723312 | 0.87 | CYP1A2 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4724172 | 0.87 | CYP1A2 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4720635 | 0.87 | MEN1 (0.42) | MEN1KMT2AALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |