SCHEMBL472311

SCHEMBL472311

CN(C)c1ccc(CCCC(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
MAPT P10636 3/20 0.61
NFKB1 P19838 2/20 0.61
TSHR P16473 2/20 0.61
GMNN O75496 1/20 0.61
LMNA P02545 1/20 0.61
CYP2D6 P10635 1/20 0.61
GABRA1 P14867 1/20 0.61
THPO P40225 1/20 0.61
GABRA2 P47869 1/20 0.61
GABRB2 P47870 1/20 0.61
PMP22 Q01453 1/20 0.61
HIF1A Q16665 1/20 0.61
SLCO1B3 Q9NPD5 1/20 0.61
HSD17B10 Q99714 2/20 0.61
MAPK1 P28482 3/20 0.60
HDAC3 O15379 1/20 0.60
ADRA1A P35348 1/20 0.60
HDAC4 P56524 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472281 0.89 FFAR1 (0.59) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL5702986 0.85 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL10102735 0.84 NR1H4 (0.70) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL6208836 0.84 SMN1; SMN2 (0.82) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL14810684 0.82 SMN1; SMN2 (0.67) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL69789 0.82 SMN1; SMN2 (0.78) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL4099468 0.80 SMN1; SMN2 (0.52) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL6310153 0.80 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL10102760 0.79 SMN1; SMN2 (0.57) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR
SCHEMBL7775748 0.79 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2MAPTNFKB1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2492746-B1 Chemically amplified negative resist composition and patterning process SHINETSU CHEMICAL CO (JP) 2019-11-20 EP disclosed
CN-105607426-B Polymer, chemical amplification negative resist composition and pattern forming method SHIN ETSU CHEMICAL COMPANY (JP) 2019-11-01 CN disclosed
EP-2492747-B1 Chemically amplified negative resist composition and patterning process SHINETSU CHEMICAL CO (JP) 2018-11-07 EP disclosed
EP-2270596-B1 Positive resist compostion and pattern forming process SHINETSU CHEMICAL CO (JP) 2018-07-25 EP disclosed
CN-104330955-B For the chemical-amplification positive anti-corrosion agent composition and patterning method of EB or EUV lithographic printings 信越化学工业株式会社 2018-05-25 CN disclosed
US-RE46765-E1 Chemically amplified negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-27 US disclosed
CN-104199255-B Chemistry amplification negative resist composition and patterning method for EB or EUV lithographic printings 信越化学工业株式会社 2018-03-13 CN disclosed
US-RE46736-E1 Chemically amplified negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
EP-2360525-B1 Chemically amplified positive resist composition and pattern forming process SHINETSU CHEMICAL CO (JP) 2017-08-23 EP disclosed
EP-2360527-B1 Patterning process using EB or EUV lithography SHINETSU CHEMICAL CO (JP) 2017-08-23 EP disclosed
EP-2202577-A1 Chemically amplified positive resist composition and resist patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2010-06-30 EP disclosed
EP-2146245-A2 Resist composition and patterning process Shinetsu Chemical Co., Ltd. (JP) 2010-01-20 EP disclosed
US-20100009299-A1 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-01-14 US disclosed
CN-101625524-A Photoresist composition and pattern forming method SHINETSU CHEMICAL CO 2010-01-13 CN disclosed
US-5607953-A ANTIISCHEMIC AGENTS EISAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0344577-B1 Butenoic or propenoic acid derivatives EISAI CO LTD (JP) 1996-10-09 EP disclosed
US-5382595-A Antiischemic agents EISAI CO., LTD. (JP) 1995-01-17 US disclosed
US-5177089-A Antiischemic agent, vasodilator EISAI CO., LTD. (JP) 1993-01-05 US disclosed
US-5047417-A Butenoic or propenoic acid derivatives EISAI CO. LTD. (JP) 1991-09-10 US disclosed
EP-0344577-A2 Butenoic or propenoic acid derivatives Eisai Co., Ltd. (JP) 1989-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009299-A1 Resist composition and patterning process ARF4, FGFR2, ARF5 ALDH1A1 2706/4885SMN1; SMN2 4381/4885MAPT 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.