Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723982 | 0.92 | GAA (0.51) | MAPTALDH1A1MAPK1HTTPOLB | |
| SCHEMBL4723252 | 0.90 | TUBB4A (0.40) | MAPTALDH1A1MAPK1HTTPOLB | |
| SCHEMBL4724361 | 0.88 | TUBB4A (0.41) | ALDH1A1POLBGAATUBB4ATUBB | |
| SCHEMBL4766563 | 0.87 | MAPT (0.52) | MAPTALDH1A1MAPK1HTTPOLB | |
| SCHEMBL4721521 | 0.87 | TUBB4A (0.42) | MAPTALDH1A1GAATUBB4ATUBB | |
| SCHEMBL4721243 | 0.85 | KDM4E (0.38) | MAPTALDH1A1HTTPOLBGAA | |
| SCHEMBL4722339 | 0.84 | HDAC1 (0.43) | POLBBACE1ADORA3ADORA2AADORA1 | |
| SCHEMBL4719745 | 0.84 | MEN1 (0.41) | MAPTALDH1A1HTTPOLBGAA | |
| SCHEMBL4722912 | 0.83 | MAPT (0.49) | MAPTALDH1A1MAPK1HTTPOLB | |
| SCHEMBL4721837 | 0.83 | CYP1A2 (0.42) | MAPTALDH1A1MAPK1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |