Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | PKLR | P30613 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 7/20 | 0.60 |
| ▸ | HTR2C | P28335 | 7/20 | 0.60 |
| ▸ | HTR2B | P41595 | 6/20 | 0.60 |
| ▸ | HTR1A | P08908 | 7/20 | 0.58 |
| ▸ | HTR6 | P50406 | 6/20 | 0.58 |
| ▸ | HTR1B | P28222 | 6/20 | 0.58 |
| ▸ | HTR1D | P28221 | 6/20 | 0.58 |
| ▸ | HTR7 | P34969 | 5/20 | 0.58 |
| ▸ | HTR5A | P47898 | 5/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.58 |
| ▸ | HTR3B | O95264 | 3/20 | 0.58 |
| ▸ | HTR1E | P28566 | 3/20 | 0.58 |
| ▸ | HTR1F | P30939 | 3/20 | 0.58 |
| ▸ | HTR3A | P46098 | 3/20 | 0.58 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.58 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.58 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.58 |
| ▸ | PTPRA | P18433 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535250 | 0.89 | NQO2 (0.62) | PKMPKLRHTR2AHTR2CHTR2B | |
| SCHEMBL7367937 | 0.88 | NQO2 (0.61) | PKMPKLRHTR2AHTR2CHTR2B | |
| SCHEMBL396020 | 0.86 | PKM (0.63) | PKMPKLRHTR2AHTR2CHTR2B | |
| SCHEMBL29507879 | 0.86 | PKM (0.63) | PKMPKLRHTR2AHTR2CHTR2B | |
| SCHEMBL11538649 | 0.85 | PKM (0.72) | PKMPKLRHTR6PTPRACYP2C19 | |
| SCHEMBL10265469 | 0.83 | PKM (0.69) | PKMPKLRPTPRACYP2C19NQO2 | |
| SCHEMBL2533742 | 0.82 | PKM (0.72) | PKMPKLRHTR2AHTR2CHTR6 | |
| SCHEMBL4721788 | 0.82 | PKM (0.72) | PKMPKLRHTR2CPTPRACYP2C19 | |
| SCHEMBL31573277 | 0.82 | PKM (0.72) | PKMPKLRHTR2AHTR2CHTR6 | |
| SCHEMBL22777992 | 0.81 | HTR2A (0.45) | PKMPKLRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883451-A2 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | Neuraxon Inc. (CA) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007063418-A2 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2007-06-07 | — | — | WO | disclosed |