Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.45 |
| ▸ | GPR6 | P46095 | 9/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385942 | 0.89 | GPR119 (0.57) | GPR119 | |
| SCHEMBL4722977 | 0.85 | GPR119 (0.55) | GPR119GPR6ACACBCHRM4 | |
| SCHEMBL4719083 | 0.83 | GPR119 (0.56) | GPR119GPR6ACACB | |
| SCHEMBL4718845 | 0.82 | GPR119 (0.63) | GPR119ACACB | |
| SCHEMBL4720606 | 0.79 | GPR119 (0.52) | GPR119ACACB | |
| SCHEMBL4719555 | 0.79 | GPR119 (0.52) | GPR119GPR6ACACB | |
| SCHEMBL4718867 | 0.78 | GPR119 (0.54) | GPR119ACACB | |
| SCHEMBL4721027 | 0.78 | GPR119 (0.55) | GPR119ACACB | |
| SCHEMBL4721995 | 0.78 | GPR119 (0.52) | GPR119GPR6ACACB | |
| SCHEMBL4721558 | 0.77 | GPR119 (0.53) | GPR119ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756084-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2008-11-26 | — | — | EP | claimed |