Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722285 | 0.74 | TRPV1 (0.31) | — | |
| SCHEMBL3540933 | 0.65 | HDAC4 (0.41) | — | |
| SCHEMBL4719957 | 0.62 | HDAC4 (0.37) | — | |
| SCHEMBL5918431 | 0.60 | SLC6A9 (0.35) | — | |
| SCHEMBL3543131 | 0.58 | SLC6A9 (0.36) | KCNQ3KCNQ2 | |
| SCHEMBL4719738 | 0.58 | P2RX7 (0.37) | — | |
| SCHEMBL5918354 | 0.56 | SLC6A9 (0.43) | KCNQ3KCNQ2 | |
| SCHEMBL3542527 | 0.56 | SLC6A9 (0.51) | KCNQ3KCNQ2 | |
| SCHEMBL3542529 | 0.56 | SLC6A9 (0.51) | KCNQ3KCNQ2 | |
| SCHEMBL3541164 | 0.56 | SLC6A9 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893566-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | MERCK SHARP & DOHME LTD. (GB) | 2008-03-05 | — | — | EP | claimed |
| WO-2006131711-A1 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA | MERCK SHARP & DOHME LIMITED (GB) | 2006-12-14 | — | — | WO | claimed |