Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101836 | 0.88 | SMN1; SMN2 (0.39) | S1PR1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL4721485 | 0.88 | ACACB (0.38) | S1PR1C5AR1LMNASMN1; SMN2MAPT | |
| SCHEMBL4721675 | 0.87 | CDK1 (0.38) | ITGB2ICAM1ITGALSOS1ABL1 | |
| SCHEMBL4721666 | 0.87 | CDK1 (0.38) | ITGB2ICAM1ITGALSOS1ABL1 | |
| SCHEMBL4720467 | 0.85 | CDK1 (0.37) | ITGB2ICAM1ITGALSOS1ABL1 | |
| SCHEMBL4720460 | 0.85 | CDK1 (0.37) | ITGB2ICAM1ITGALSOS1ABL1 | |
| SCHEMBL4719061 | 0.80 | ITGB2 (0.35) | ITGB2ICAM1ITGALSOS1ABL1 | |
| SCHEMBL4719067 | 0.80 | ITGB2 (0.35) | ITGB2ICAM1ITGALSOS1ABL1 | |
| SCHEMBL4720518 | 0.80 | ITGB2 (0.35) | ITGB2ICAM1ITGALSOS1ABL1 | |
| SCHEMBL4720760 | 0.80 | CDK1 (0.35) | ITGB2ICAM1ITGALSOS1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |