Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723487 | 0.88 | ITGB2 (0.36) | SMN1; SMN2LMNAHTTRECQLMAPT | |
| SCHEMBL14102029 | 0.85 | ACHE (0.40) | SMN1; SMN2LMNAHTTRECQLACHE | |
| SCHEMBL4721485 | 0.84 | ACACB (0.38) | SMN1; SMN2LMNADCTPP1MAPTKMT2A | |
| SCHEMBL14102034 | 0.83 | KDM4E (0.37) | SMN1; SMN2LMNAACHEDCTPP1MAPT | |
| SCHEMBL14101743 | 0.77 | HTR2A (0.36) | SMN1; SMN2LMNAHTTMAPTKDM4E | |
| SCHEMBL14101744 | 0.76 | AKR1B10 (0.35) | LMNAHTTMAPTKDM4EHSD17B10 | |
| SCHEMBL4721666 | 0.73 | CDK1 (0.38) | LMNADCTPP1MAPTKDM4ENPSR1 | |
| SCHEMBL4721675 | 0.73 | CDK1 (0.38) | LMNADCTPP1MAPTKDM4ENPSR1 | |
| SCHEMBL4724195 | 0.73 | F10 (0.42) | HTTMAPTHRH3ALDH1A1F2 | |
| SCHEMBL4722495 | 0.72 | F10 (0.44) | HTTMAPTHRH3KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |