Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8267993 | 0.85 | GABRA1 (0.59) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL12500189 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL1432756 | 0.82 | GABRA1 (0.65) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL1691670 | 0.82 | GABRA1 (0.65) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL1430476 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL4253068 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL29621620 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2KDM4ELMNAALB | |
| Dimethylamine SCHEMBL5629018 | 0.81 | TP53 (0.61) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL4253085 | 0.81 | GABRA1 (0.54) | GABRA1GABRB2KDM4ELMNAALB | |
| Hydrochloric Acid SCHEMBL1430106 | 0.81 | GABRA1 (0.60) | GABRA1GABRB2KDM4ELMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293947-A1 | Method of Preparation for Imidazolepyridines | MALLINCKRODT INC. | 2008-11-27 | — | — | US | disclosed |
| EP-1966201-A1 | IMPROVED METHOD OF PREPARATION FOR IMIDAZOLEPYRIDINES | Mallinckrodt, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1539751-B1 | PROCESS FOR THE PREPARATION OF IMIDAZO(1,2-A)PYRIDINE-3-ACETAMIDES | SCINOPHARM TAIWAN LTD (TW) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007064444-A1 | IMPROVED METHOD OF PREPARATION FOR IMIDAZOLEPYRIDINES | MALLINCKRODT INC. (US) | 2007-06-07 | — | — | WO | disclosed |
| US-6861525-B2 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | SCINOPHARM TAIWAN, LTD. (TW) | 2005-03-01 | — | — | US | disclosed |
| US-20040010146-A1 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | SCINOPHARM TAIWAN, LTD. | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293947-A1 | Method of Preparation for Imidazolepyridines | ITPA, QDPR, NISCH | GABRA1 936/4885GABRB2 1413/4885KDM4E 1146/4885 |
| US-20040010146-A1 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | AAK1, ACP3, AP2M1 | GABRA1 332/4885GABRB2 1128/4885KDM4E 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.