Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.47 |
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SDHA | P31040 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766969 | 0.82 | CALML3 (0.50) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7004283 | 0.82 | CALML3 (0.48) | CALML3MAOAMAOBCYP3A4CYP2D6 | |
| SCHEMBL4724953 | 0.80 | GRM2 (0.44) | CALML3 | |
| SCHEMBL6996606 | 0.80 | MAOA (0.45) | CALML3MAOAMAOBCYP3A4 | |
| SCHEMBL10062439 | 0.78 | CALML3 (0.67) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL542030 | 0.78 | CALML3 (0.67) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL542031 | 0.78 | CALML3 (0.67) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL17769239 | 0.77 | CALML3 (0.53) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL17769240 | 0.77 | CALML3 (0.53) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL4166930 | 0.75 | MAOA (0.66) | CALML3MAOAMAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931684-A2 | OXAZOLIDINONE-QUINOLONE HYBRIDS AS ANTIBACTERIAL COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007017828-A2 | OXAZOLIDINONE-QUINOLONE HYBRIDS AS ANTIBACTERIAL COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-02-15 | — | — | WO | disclosed |