Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723700 | 1.00 | P2RX7 (0.43) | P2RX7KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL4722881 | 0.91 | HSD11B1 (0.41) | P2RX7KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL4722888 | 0.91 | HSD11B1 (0.41) | P2RX7KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL4721415 | 0.91 | P2RX7 (0.40) | P2RX7ALDH1A1LMNAMAPK1RORC | |
| SCHEMBL4721412 | 0.91 | P2RX7 (0.40) | P2RX7ALDH1A1LMNAMAPK1RORC | |
| SCHEMBL4722700 | 0.91 | P2RX7 (0.41) | P2RX7KDM4ERORCNOTUMPDE3B | |
| SCHEMBL4722703 | 0.91 | P2RX7 (0.41) | P2RX7KDM4ERORCNOTUMPDE3B | |
| SCHEMBL4721099 | 0.91 | P2RX7 (0.41) | P2RX7RORCNOTUMHSD11B1PDE3B | |
| SCHEMBL4721096 | 0.91 | P2RX7 (0.41) | P2RX7RORCNOTUMHSD11B1PDE3B | |
| SCHEMBL4766685 | 0.90 | P2RX7 (0.43) | P2RX7KDM4ELMNARORCHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |