SCHEMBL4723899

SCHEMBL4723899

CS(=O)(=O)c1ccc(N2CC[C@H](O)C2)cc1-n1nc(-c2cc(Br)cc(-c3cnco3)c2)c2cccnc2c1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.33
PIM1 P11309 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4723905 1.00 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4719871 0.94 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4722421 0.94 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4719872 0.94 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4723974 0.93 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4723970 0.93 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4719615 0.92 SLC40A1 (0.32) SLC40A1
SCHEMBL4719012 0.88 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4719010 0.88 SLC40A1 (0.33) SLC40A1PIM1
SCHEMBL4720512 0.82 SLC40A1 (0.35) SLC40A1PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1953147-A1 HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF Japan Tobacco, Inc. (JP) 2008-08-06 EP disclosed
EP-1953147-A1 HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF Japan Tobacco, Inc. (JP) 2008-08-06 EP disclosed