Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.30 |
| ▸ | MYC | P01106 | 2/20 | 0.30 |
| ▸ | WDR5 | P61964 | 2/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723922 | 1.00 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3AHSD11B1 | |
| SCHEMBL4723917 | 1.00 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3AHSD11B1 | |
| SCHEMBL4722487 | 0.91 | P2RX7 (0.38) | P2RX7SOS1PDE3BPDE3AHSD11B1 | |
| SCHEMBL4722494 | 0.91 | P2RX7 (0.38) | P2RX7SOS1PDE3BPDE3AHSD11B1 | |
| SCHEMBL4720488 | 0.84 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4720492 | 0.84 | P2RX7 (0.34) | P2RX7SOS1PDE3BPDE3APHGDH | |
| SCHEMBL4721441 | 0.81 | SYK (0.42) | P2RX7SOS1PDE3BPDE3AHSD11B1 | |
| SCHEMBL4721436 | 0.81 | SYK (0.42) | P2RX7SOS1PDE3BPDE3AHSD11B1 | |
| SCHEMBL4722499 | 0.79 | SCN5A (0.31) | — | |
| SCHEMBL4722501 | 0.79 | SCN5A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |