⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724340 | 0.91 | — | — | |
| SCHEMBL4722403 | 0.90 | — | — | |
| SCHEMBL4724456 | 0.84 | TDP1 (0.31) | — | |
| SCHEMBL28875541 | 0.80 | DNM1 (0.42) | — | |
| SCHEMBL4724081 | 0.77 | — | — | |
| SCHEMBL4765517 | 0.76 | — | — | |
| SCHEMBL4721030 | 0.75 | — | — | |
| SCHEMBL27809734 | 0.74 | P2RX1 (0.31) | — | |
| SCHEMBL17731674 | 0.70 | — | — | |
| SCHEMBL4724562 | 0.67 | DNM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC. | 2008-07-24 | — | — | US | disclosed |
| EP-1874780-A1 | 4-PIPERAZINYLTHIENO[2,3-D]PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006100591-A1 | 4-PIPERAZINNYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| EP-0354018-B1 | An electrodeposition coating composition and image-forming method using the same | NIPPON PAINT CO LTD (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5055374-A | Positive working resist | NIPPON PAINT CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0354018-A2 | An electrodeposition coating composition and image-forming method using the same | NIPPON PAINT CO., LTD. (JP) | 1990-02-07 | — | — | EP | disclosed |