SCHEMBL28875541

SCHEMBL28875541

CCCCCCN(CCCCCC)n1cccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.42
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
GPR84 Q9NQS5 2/20 0.36
KCNH2 Q12809 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
GBA1 P04062 1/20 0.32
NPC1 O15118 1/20 0.32
JAK2 O60674 1/20 0.32
RAB9A P51151 1/20 0.32
PAX8 Q06710 1/20 0.32
MGLL Q99685 1/20 0.31
TBXAS1 P24557 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4724456 0.91 TDP1 (0.31)
SCHEMBL4724340 0.86
SCHEMBL4721030 0.82
SCHEMBL7975725 0.71 ADH1C (0.38) DNM1TSHRNPC1JAK2RAB9A
SCHEMBL11573150 0.71 DNM1 (0.32) DNM1
SCHEMBL4724562 0.70 DNM1 (0.33) DNM1GPR84
Heptane SCHEMBL28254518 0.67 TSHR (0.47) TSHRTHRBKCNH2NPC1RAB9A
Octane SCHEMBL28301548 0.67 TSHR (0.47) TSHRTHRBKCNH2NPC1RAB9A
Octane SCHEMBL28253594 0.67 TSHR (0.47) TSHRTHRBKCNH2NPC1RAB9A
Heptane SCHEMBL28253586 0.67 TSHR (0.47) TSHRTHRBKCNH2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110139851-A The adduct formed by the carbon allotrope of primary amine, Dicarbonyl derivatives, inorganic oxide hydroxide and SP2- hydridization 倍耐力轮胎股份公司 2019-08-16 CN disclosed