Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 3/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101709 | 0.94 | F10 (0.39) | F10F2SLC16A3SLC16A1MAPT | |
| SCHEMBL4722372 | 0.93 | F10 (0.38) | F10F2SLC16A3SLC16A1MAPT | |
| SCHEMBL4724288 | 0.91 | F10 (0.40) | F10F2SLC16A3SLC16A1MAPT | |
| SCHEMBL14101737 | 0.90 | CCR1 (0.39) | F10F2MAPTCCR1 | |
| SCHEMBL14101703 | 0.90 | F10 (0.36) | F10F2SLC16A3SLC16A1MAPT | |
| SCHEMBL4720721 | 0.90 | F10 (0.36) | F10F2CXCR3 | |
| SCHEMBL4720716 | 0.90 | F10 (0.36) | F10F2CXCR3 | |
| SCHEMBL4720459 | 0.88 | F10 (0.40) | F10F2SLC16A3SLC16A1MAPT | |
| SCHEMBL4720196 | 0.87 | TDP1 (0.38) | F10F2MAPTCCR1CXCR3 | |
| SCHEMBL14101989 | 0.86 | ADRA1D (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |