Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101712 | 0.94 | F10 (0.39) | F10F2SLC16A3SLC16A1CCR1 | |
| SCHEMBL4722372 | 0.93 | F10 (0.38) | F10F2SLC16A3SLC16A1CCR1 | |
| SCHEMBL4724288 | 0.91 | F10 (0.40) | F10F2SLC16A3SLC16A1MAPT | |
| SCHEMBL14101703 | 0.90 | F10 (0.36) | F10F2SLC16A3SLC16A1MAPT | |
| SCHEMBL14101737 | 0.90 | CCR1 (0.39) | F10F2CCR1MAPT | |
| SCHEMBL4721921 | 0.90 | CXCR3 (0.33) | F10F2CCR1MAPTALPL | |
| SCHEMBL4720618 | 0.90 | F10 (0.36) | F10F2S1PR1CXCR3 | |
| SCHEMBL4720620 | 0.90 | F10 (0.36) | F10F2S1PR1CXCR3 | |
| SCHEMBL4720926 | 0.89 | WDR5 (0.33) | F10SLC16A3SLC16A1MAPTALPL | |
| SCHEMBL4720196 | 0.87 | TDP1 (0.38) | F10F2CCR1MAPTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |