Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119066 | 0.81 | BCHE (0.56) | NOTUMHSD17B3NPSR1POLBSMN1; SMN2 | |
| SCHEMBL1754049 | 0.79 | NOTUM (0.53) | NOTUMHSD17B3POLBKDM4ESMN1; SMN2 | |
| SCHEMBL28307229 | 0.78 | BCHE (0.58) | NOTUMPOLBKDM4ESMN1; SMN2BCHE | |
| SCHEMBL5026715 | 0.77 | NOTUM (0.51) | NOTUMHSD17B3KDM4ESMN1; SMN2BCHE | |
| Hydrochloric Acid SCHEMBL27756629 | 0.77 | NOTUM (0.51) | NOTUMHSD17B3POLBKDM4ESMN1; SMN2 | |
| SCHEMBL11407839 | 0.77 | BCHE (0.54) | NOTUMHSD17B3POLBKDM4ESMN1; SMN2 | |
| Acetic Acid SCHEMBL5028762 | 0.75 | NOTUM (0.54) | NOTUMHSD17B3POLBKDM4ESMN1; SMN2 | |
| SCHEMBL11193164 | 0.75 | NOTUM (0.49) | NOTUMHSD17B3POLBKDM4ESMN1; SMN2 | |
| SCHEMBL21765696 | 0.74 | POLB (0.57) | NOTUMNPSR1POLBKDM4EHTT | |
| SCHEMBL4629227 | 0.74 | NOTUM (0.44) | NOTUMHSD17B3NPSR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1998741-A1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | UNILEVER PLC (GB) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007112854-A1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | UNILEVER PLC (GB) | 2007-10-11 | — | — | WO | disclosed |