Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724001 | 0.89 | PDE4A (0.36) | NOTUMPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4719842 | 0.88 | PDE4A (0.38) | NOTUMPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4720712 | 0.86 | — | — | |
| SCHEMBL4721383 | 0.86 | BRD4 (0.32) | — | |
| SCHEMBL4723242 | 0.85 | — | — | |
| SCHEMBL4719140 | 0.84 | — | — | |
| SCHEMBL4723635 | 0.84 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4766566 | 0.82 | — | — | |
| SCHEMBL4719532 | 0.79 | PDE4A (0.38) | NOTUMPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4723419 | 0.79 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |