Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | GCGR | P47871 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339213 | 0.88 | IDO1 (0.38) | DPP4EPHX2SMN1; SMN2HPGDMAPK8 | |
| SCHEMBL339235 | 0.84 | DPP4 (0.43) | DPP4 | |
| SCHEMBL340129 | 0.81 | ALDH1A1 (0.39) | DPP4SMN1; SMN2HPGDMAPK8 | |
| SCHEMBL339781 | 0.78 | ALDH1A1 (0.38) | DPP4SMN1; SMN2HPGDMAPK8LMNA | |
| SCHEMBL339323 | 0.78 | ALDH1A1 (0.38) | EPHX2SMN1; SMN2HPGDMAPK8 | |
| SCHEMBL338930 | 0.76 | CRHR1 (0.41) | DPP4SMN1; SMN2HPGDLMNA | |
| SCHEMBL340037 | 0.74 | DPP4 (0.39) | DPP4CNR1LMNA | |
| SCHEMBL339494 | 0.74 | SLC2A1 (0.43) | DPP4SMN1; SMN2HPGDLMNA | |
| SCHEMBL339357 | 0.74 | CRHR1 (0.39) | DPP4LMNA | |
| SCHEMBL1913178 | 0.74 | PAK3 (0.41) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004643-A1 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007113226-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-10-11 | — | — | WO | disclosed |